Volume 642 Issue 8068, 19 June 2025
https://www.nature.com/nature/volumes/642/issues/8068
Editorial 社论
In science’s new era, open and transparent cooperation remains key
《科学新时代中，开放透明的合作仍是关键》
Transparent peer review to be extended to all of Nature’s research papers
《Nature将全面推广透明同行评审至所有研究论文》
World View 全球观点
Could a novelty indicator improve science?
《新颖性指标能否推动科学发展？》
Why air-traffic controller shortages are not to blame for US airport chaos
《美国机场混乱并非空管人员短缺之过》
PhD students face high risk of sexual harassment — can universities stop perpetrators?
《博士生面临高风险性骚扰，大学能否遏制施害者？》
Research Highlights 研究亮点
Minuscule worms form living towers to hunt for food
《微小蠕虫构筑“活体高塔”捕食》
Hungry caterpillars can brew exotic molecules in their guts
《饥饿毛毛虫肠道可酿造特殊分子》
A cancer-causing mutation meets its match
《致癌突变遭遇克星》
A long-predicted cosmic collision might not happen after all
《预言已久的星系碰撞或终将落空》
News in Focus 焦点新闻
Major telescope hosts world’s largest digital camera: how it will transform astronomy
《大型望远镜搭载全球最大数码相机，如何变革天文学》
How the brain separates real images from those it imagines
《大脑如何区分真实与想象图像》
Skyrocketing mpox outbreak in Sierra Leone raises fears of wider spread
《塞拉利昂猴痘病例激增引广泛传播担忧》
Exclusive: Start-up FutureHouse debuts powerful AI ‘reasoning model’ for science
《独家：初创公司FutureHouse推出科学用AI“推理模型”ether0》
‘Another blow’: how Trump’s latest travel ban could harm research
《特朗普新旅行禁令冲击科研合作》
Africa has a new space agency — here’s what it will do
《非洲新航天局的使命蓝图》
How China is vying to attract the world’s top scientific talent
《中国如何竞逐全球顶尖科研人才》
Features 特写
Is a monster web of ocean currents headed for collapse? The race is on to find out
《巨型洋流网濒临崩溃？科学家竞相求解》
How your brain controls ageing — and why zombie cells could be key
《大脑如何调控衰老：僵尸细胞或是关键》
Books & Arts 书评与艺术
‘One of the true final frontiers’ — Sally Ride biopic highlights the struggle of gay astronauts
《〈真实的最后边疆〉：Sally Ride传记片揭示同性恋宇航员的抗争》
Opinion 观点
Obituary 讣告
Peter Lax obituary: mathematician who pioneered computer-based solutions
《彼得·拉克斯：用计算机破解现实难题的数学先驱》
Comment 评论
How China can become a biotechnology superpower
《中国如何成为生物技术超级大国》
After decades of pioneering institutional change in Chinese research, neuroscientist Rao Yi explains why US hesitation might offer China an opportunity to catch up internationally.
Correspondence 读者来信
Is there a link between gut microbes and ageing?
《肠道微生物与衰老是否存在关联？》
Tighter regulation is needed for AI companions
《AI伴侣需加强监管》
US–China trade conflict threatens biomedical collaboration
《中美贸易冲突危及生物医学合作》
We need to show AI what didn’t work as well as what did
《AI需学习失败与成功经验》
Work 职场
Authorship for sale: Nature investigates how paper mills work
《待售的作者署名：Nature深挖论文工厂运作》
Freeze frame: cracking molecular motion
《定格瞬间：破解分子运动》
I can’t show my face because of pangolin poachers
《穿山甲盗猎者迫使我的匿名人生》
Research 研究
News & Views 新闻与观点
How axolotl cells ‘remember’ development to rebuild a lost limb
《蝾螈细胞如何“记忆”发育以再生断肢》
Trace elements in the ocean attributed to a surprising source
《海洋微量元素溯源颠覆传统认知》
Under the microscope: DNA damage tracked through cell generations
《显微追踪：DNA损伤的细胞代际传递》
Light detectors made from perovskite crystals see in full colour
《钙钛矿晶体全彩色光探测器问世》
Fetal and parental genomes offer mechanistic insights into pregnancy loss
《胎儿与父母基因组揭示早期流产机制》
对经历早期流产的 母亲-父亲-胎儿 三人组 的基因组分析，揭示了染色体异常和潜在遗传变异的影响。
每一次活产都是在克服重重困难的情况下发生的，因为在人类繁殖过程中，许多事情都可能—而且经常—出错。自然流产在人类中非常常见，影响了大约15%的临床认可的妊娠，还有相当一部分在临床认可之前就已经流产。尽管存在这种普遍性和几种已知的早期流产原因，但许多流产仍然无法解释，这加剧了父母的痛苦，并阻碍了对未来怀孕的准确风险评估。Arnadottir 等人在《自然》杂志上发表了一项关于早期妊娠丢失的全面基因组研究。他们对数百个流产的胎儿基因组以及父母基因组进行了测序，并在大约55%的病例中确定了可能的遗传原因，说明了遗传在生殖和早期发育过程中可能出错的许多方式。
关联文章 (见下文)：《早期妊娠中丢失的序列多样性》
相关研究思路和分析方法 (短变异检测)，见易生信课程：
https://www.bic.ac.cn/Training/fore/#/?pageName=CourseDetails&ID=105
Articles 研究论文
Detection of X-ray emission from a bright long-period radio transient
《长周期射电瞬变源的X射线辐射探测》
Integrated photonic source of Gottesman–Kitaev–Preskill qubits
《GKP量子比特的集成光子源》
Vertically stacked monolithic perovskite colour photodetectors
《垂直堆叠单片钙钛矿彩色光电探测器》
Light-triggered regionally controlled n-doping of organic semiconductors
《光触发有机半导体区域可控n型掺杂》
Acetolysis for epoxy-amine carbon fibre-reinforced polymer recycling
《乙酸解聚回收环氧胺碳纤维增强聚合物》
Abyssal seafloor as a key driver of ocean trace-metal biogeochemical cycles
《深海海底驱动海洋痕量金属生物地球化学循环》
Warming accelerates global drought severity
《气候变暖加剧全球干旱严重性》
Drivers of the extreme North Atlantic marine heatwave during 2023
《2023年北大西洋极端海洋热浪成因》
Impacts of climate change on global agriculture accounting for adaptation
《适应性措施下的气候变化对全球农业影响》
Plant diversity dynamics over space and time in a warming Arctic
《北极变暖中植物多样性的时空动态》
A pangenome reference of wild and cultivated rice
《野生与栽培水稻泛基因组参考图谱》
Sequence diversity lost in early pregnancy
《早期妊娠中丢失的序列多样性》
https://doi.org/10.1038/s41586-025-09031-w
Fig. 1 | Sequencing overview and fetal presence in pregnancy loss samples. a, Flowchart of the study. b, The gestational ages of fetal samples. The gestational age was estimated as the time difference from the last menstruation to the date of pregnancy loss. c, The paternal fraction of fetal samples. The paternal fraction is shown for intervals of gestational age estimated on the basis of the last menstruation (GA–LM): weeks 0–9, weeks 9–12 and weeks 12–22. d, Kinship between fetal and parental samples. There are 26 (11 pregnancy loss cases) and 93 (59 pregnancy loss cases) fetal samples that had higher than expected kinship with their father and mother, respectively. Furthermore, there are 27 (11 pregnancy loss cases) and 42 (19 pregnancy loss cases) fetal samples from paternal and maternal triploidies, respectively.
Fig. 2 | Maternal triploidy example. a, Schematic of meiosis II error. Meiosis I error is shown in Extended Data Fig. 1. b, Maternal crossovers at chromosome 2 for a triploid fetus. The phase-informative sequence variants in the fetal genome are informative about transitions between the homologous chromosome and sister chromatid states along the genome. The phase-informative variants are limited to heterozygous (0/1) variants in the mother (1 is the HS allele). In the homologous state, the maternal variants are always present in the fetal genome (0/0/1), as both of the maternal haplotypes are present. In the sister state, the maternal variants are either absent (0/0/0) or have an allelic balance of 2/3 (0/1/1).
Multi-timescale reinforcement learning in the brain
《大脑中的多时间尺度强化学习》
Molecular basis of positional memory in limb regeneration
《肢体再生位置记忆的分子基础》
A MERS-CoV-like mink coronavirus uses ACE2 as an entry receptor
《类MERS-CoV貂冠状病毒利用ACE2作为入侵受体》
Matters Arising 争议
On the effects of fault alignment on slip stability
《断层对齐对滑动稳定性的影响》
Reply to: On the effects of fault alignment on slip stability
《回应“断层对齐对滑动稳定性的影响”》
Amendments & Corrections 修正
Author Correction: Methane oxidation to ethanol by a molecular junction photocatalyst
《作者修正：分子结光催化剂将甲烷氧化为乙醇》
Publisher Correction: Metal–support frontier orbital interactions in single-atom catalysis
《出版方修正：单原子催化中金属-载体前沿轨道相互作用》
机器学习